Follow I-40 E, I-95 S And Us-74 E To Nc-130 E/Nc-410 S In Columbus County. Take The Exit Toward Chadbourn From Us-74 E, Get On Sc-22 E In Horry County From Us-701 Hwy, Sc-66 S And Red Bluff Rd, Follow Sc-22 E To Us-17 S. Take The Us-17 S Exit From Sc-22 E, Continue On Us-17 S To Your Destination In Myrtle Beach